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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TP53RK
All Species:
10.91
Human Site:
T135
Identified Species:
21.82
UniProt:
Q96S44
Number Species:
11
Phosphosite Substitution
Charge Score:
0.36
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96S44
NP_291028.3
253
28160
T135
S
T
M
E
T
E
K
T
P
Q
G
L
S
N
L
Chimpanzee
Pan troglodytes
XP_514697
253
28128
T135
S
T
M
E
T
E
K
T
P
Q
G
L
S
N
L
Rhesus Macaque
Macaca mulatta
XP_001107480
201
22218
R100
T
I
G
Q
V
L
A
R
M
H
D
E
D
L
I
Dog
Lupus familis
XP_853966
302
33650
T184
S
T
M
E
T
E
K
T
P
Q
S
L
L
S
L
Cat
Felis silvestris
Mouse
Mus musculus
Q99PW4
244
27375
D126
S
T
M
E
T
E
K
D
P
Q
C
L
L
D
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_425703
314
33606
D196
S
V
Q
R
S
G
S
D
A
S
S
L
L
G
L
Frog
Xenopus laevis
NP_001089506
237
26742
E119
S
M
Q
Q
S
G
K
E
T
S
S
L
N
A
L
Zebra Danio
Brachydanio rerio
NP_001018386
231
26056
T117
S
Q
P
D
G
L
Q
T
L
A
E
R
I
G
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_647948
224
25346
F112
A
K
K
C
L
L
E
F
C
T
R
I
G
E
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002300825
226
25241
E111
F
G
L
N
G
V
V
E
E
R
L
D
D
I
A
Maize
Zea mays
NP_001146448
226
25230
E111
F
G
S
D
G
V
N
E
E
R
L
N
D
I
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53323
261
29918
S135
M
H
D
Q
D
P
Y
S
D
L
V
A
T
T
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
68.3
78.4
N.A.
83.7
N.A.
N.A.
N.A.
56.3
66
61.2
N.A.
41.5
N.A.
N.A.
N.A.
Protein Similarity:
100
100
71.9
81.1
N.A.
88.9
N.A.
N.A.
N.A.
66.2
78.2
77.4
N.A.
56.9
N.A.
N.A.
N.A.
P-Site Identity:
100
100
0
80
N.A.
73.3
N.A.
N.A.
N.A.
20
26.6
13.3
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
20
86.6
N.A.
80
N.A.
N.A.
N.A.
26.6
46.6
26.6
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
44.2
41.9
N.A.
N.A.
32.1
N.A.
Protein Similarity:
60.4
58.1
N.A.
N.A.
48.6
N.A.
P-Site Identity:
0
0
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
13.3
13.3
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
0
0
9
0
9
9
0
9
0
9
17
% A
% Cys:
0
0
0
9
0
0
0
0
9
0
9
0
0
0
0
% C
% Asp:
0
0
9
17
9
0
0
17
9
0
9
9
25
9
0
% D
% Glu:
0
0
0
34
0
34
9
25
17
0
9
9
0
9
9
% E
% Phe:
17
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% F
% Gly:
0
17
9
0
25
17
0
0
0
0
17
0
9
17
0
% G
% His:
0
9
0
0
0
0
0
0
0
9
0
0
0
0
0
% H
% Ile:
0
9
0
0
0
0
0
0
0
0
0
9
9
17
17
% I
% Lys:
0
9
9
0
0
0
42
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
9
0
9
25
0
0
9
9
17
50
25
9
59
% L
% Met:
9
9
34
0
0
0
0
0
9
0
0
0
0
0
0
% M
% Asn:
0
0
0
9
0
0
9
0
0
0
0
9
9
17
0
% N
% Pro:
0
0
9
0
0
9
0
0
34
0
0
0
0
0
0
% P
% Gln:
0
9
17
25
0
0
9
0
0
34
0
0
0
0
0
% Q
% Arg:
0
0
0
9
0
0
0
9
0
17
9
9
0
0
0
% R
% Ser:
59
0
9
0
17
0
9
9
0
17
25
0
17
9
0
% S
% Thr:
9
34
0
0
34
0
0
34
9
9
0
0
9
9
0
% T
% Val:
0
9
0
0
9
17
9
0
0
0
9
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _